KEGG Drug Group

KEGG DGROUP contains structurally and functionally related groups of D number entries in KEGG DRUG. There are five types of drug groups. Chemical - grouped as identical chemical structures with minor variations of salts, hydration states, etc. Structure - grouped as similar chemical structures having the same skeleton, etc. Target - grouped by drug targets Class - drug classes often representing similar mechanisms of action Metabolism - grouped by substrates, inhibitors and inducers of drug metabolizing enzymes and transporters Chemical groups are often used for identifying essentially the same active ingredients of drugs in different countries.