Find open-source science resources

Cross-domain directory aggregating tools, AI models, datasets, and research resources from bio.tools, Bioconductor, HuggingFace, curated GitHub awesome-lists, and more.

5,674 resources indexed

Showing 301350

Apertus-70B-MeditronFO is a 70B-parameter medical specialist LLM, produced by supervised fine-tuning of Apertus-70B-Instruct on the Fully Open Meditron Corpus.

3971 week ago
Python
6.2K3 weeks ago

Meow-Omni 1 is the world’s first Multimodal Large Language Model (MLLM) specifically engineered for Computational Ethology. It natively co-embeds four distinct modalities—Text, Video, Audio, and Biological Time-Series—to decode the latent intentions of non-verbal species.

2521 week ago

# Model details ## Model description Nature Language Model (NatureLM) is a sequence-based science foundation model designed for scientific discovery. Pre-trained with data from multiple scientific domains, NatureLM offers a unified, versatile model that enables various applications including…

24011 months ago

# Model details ## Model description Nature Language Model (NatureLM) is a sequence-based science foundation model designed for scientific discovery. Pre-trained with data from multiple scientific domains, NatureLM offers a unified, versatile model that enables various applications including…

3311 months ago

vitreg4so150mp14ls_dino-v2-bio is a Bio-DINO image encoder for natural photographs of living organisms. It uses a SoViT-150M/14 Vision Transformer with 4 register tokens and 133.6M backbone parameters, trained with a DINOv2-style self-supervised objective on approximately 31 million curated images…

3.9K3 days ago

Curated open dataset collection of 602M+ observational and perturbational single-cell profiles for accelerating virtual cell model creation, integrating Tahoe-100M and scBaseCount data with Google Cloud Marketplace distribution (Arc Institute, 2025-2026)

Probabilistic framework for inferring cell fate decisions and trajectory dynamics from multi-view single-cell data using Markov chains and machine learning, integrating RNA velocity, pseudotime, and metabolic labeling to predict differentiation paths and terminal states (scverse/Theis Lab, 449+ stars, BSD 3-Clause)

Google DeepMind's official collection of agentic science skills accelerating scientific workflows with better grounding and higher token efficiency, integrating insights from AlphaGenome, AFDB, UniProt and 30+ other databases and tools (2026)

An ontology that enables the metadata properties of the DataCite Metadata Schema Specification (i.e., a list of metadata properties for the accurate and consistent identification of a resource for citation and retrieval purposes) to be described in RDF.

41 week ago
XSLT
05 years ago
33 years ago
Makefile

A data model for managing information about chemical entities, ranging from atoms through molecules to complex mixtures.

233 days ago
Python
CC0-1.0

The covid-19 epidemiology and monitoring ontology (cemo) provides a common ontological model to make epidemiological quantitative data for monitoring the covid-19 outbreak machine-readable and interoperable to facilitate its exchange, integration and analysis, to eventually support evidence-based rapid response.

73 years ago
TeX
CC0-1.0

CCSO is an educational ontology acting as a data model for concepts and entities within an academic setting, enabling also the annotation of potentially available resources. The ontology aims to conceptualize educational entities within Curriculum and Syllabus with appropriate coverage and quality, in order to support rich services on top for improving curriculum management and automatically enabling syllabus semantic processes. (from homepage)

05 months ago
HTML
GPL-3.0

An ontology that permits the number of in-text citations of a cited source to be recorded, together with their textual citation contexts, along with the number of citations a cited entity has received globally on a particular date.

06 years ago

An extension of Schema.org to annotate metadata on software projects

3481 month ago
Python
Apache-2.0

An ontology meant to define bibliographic records, bibliographic references, and their compilation into bibliographic collections and bibliographic lists, respectively.

06 years ago

An ontology that allows the description of numerical and categorical bibliometric data (e.g., journal impact factor, author h-index, categories describing research careers) in RDF.

06 years ago

Babelon is a simple standard for managing ontology translations and language profiles. Profiles are managed as TSV files, see for example https://github.com/obophenotype/hpo-translations/tree/main/babelon. The goal of Babelon as a data model and vocabulary is to capture the minimum data required to capture important metadata such as confidence and precision of translation.

102 months ago
Jupyter Notebook
MIT

An EMMO-based domain ontology for atomistic and electronic modelling.

12 months ago
Python
CC-BY-4.0

A representation of variables appearing in models in the environmental research space.

45 days ago
HTML

Algorithm Metadata Vocabulary is a vocabulary for capturing and storing the metadata about the algorithms (a procedure or a set of rules that is followed step-by-step to solve a problem, especially by a computer). There are uncountable algorithms present in every area (e.g., Computer Science, Mathematics), which makes it hard for specialists, academicians, application engineers, and so forth to discover, distinguish, select, and reuse them. [from repository]

03 years ago
Python
CC0-1.0

The academic event ontology, currently still in development and thus unstable, is an OBO compliant reference ontology for describing academic events such as conferences, workshops or seminars and their series. It is being developed as part of the [ConfIDent project](https://projects.tib.eu/confident/) to allow RDF representations of the academic events and series stored and curated in the [ConfIDent platform](https://www.confident-conference.org/index.php/main_page).

141 year ago
Makefile
CC-BY-4.0

This ontology models classes and relationships describing deep learning networks, their component layers and activation functions, as well as potential biases.

491 year ago
Jupyter Notebook
52 weeks ago
Python

Stereoscope is a variational inference model for single-cell RNA-seq data that can learn a cell-type specific rate of gene expression. The predictions of the model are meant to be afterward used for deconvolution of a second spatial transcriptomics dataset in Stereoscope.

02 months ago

ScANVI is a variational inference model for single-cell RNA-seq data that can learn an underlying latent space, integrate technical batches and impute dropouts. In addition, to scVI, ScANVI is a semi-supervised model that can leverage labeled data to learn a cell-type classifier in the latent space…

02 months ago

Stereoscope is a variational inference model for single-cell RNA-seq data that can learn a cell-type specific rate of gene expression. The predictions of the model are meant to be afterward used for deconvolution of a second spatial transcriptomics dataset in Stereoscope.

02 months ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-TOXCAST-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

51 year ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-TOX21-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

131 year ago

In recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more effectively treat specific domains.

3572 years ago
Python

In recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more effectively treat specific domains.

02 years ago
Python
03 years ago

This is a ReactionT5 pre-trained to predict the products of reactions.

631 year ago
Python

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82 months ago
Python

This repository contains the official model of the paper A Unified Predictive and Generative Solution for Liquid Electrolyte Formulation.

09 months ago

Github | Cite

32 months ago

InstaNovoPlus is a diffusion-based model for de novo peptide sequencing from mass spectrometry data. This model leverages multinomial diffusion for accurate, database-free peptide identification for large-scale proteomics experiments.

47 months ago

Winnow recalibrates confidence scores and provides FDR control for de novo peptide sequencing (DNS) workflows. This repository contains the calibrator trained on HeLa Single Shot data as referenced in our paper: De novo peptide sequencing rescoring and FDR estimation with Winnow.

02 weeks ago

Winnow recalibrates confidence scores and provides FDR control for de novo peptide sequencing (DNS) workflows. This repository hosts a pretrained, general-purpose calibrator that maps raw InstaNovo model confidences and complementary features (mass error, retention time, chimericity, beam features,…

02 weeks ago

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

311 months ago
Python

PPTStab: Prediction and Designing of thermostable proteins with a desired melting temperature

01 year ago
Python

ScANVI is a variational inference model for single-cell RNA-seq data that can learn an underlying latent space, integrate technical batches and impute dropouts. In addition, to scVI, ScANVI is a semi-supervised model that can leverage labeled data to learn a cell-type classifier in the latent space…

02 months ago

ScVI is a variational inference model for single-cell RNA-seq data that can learn an underlying latent space, integrate technical batches and impute dropouts. The learned low-dimensional latent representation of the data can be used for visualization and clustering.

02 months ago

Stereoscope is a variational inference model for single-cell RNA-seq data that can learn a cell-type specific rate of gene expression. The predictions of the model are meant to be afterward used for deconvolution of a second spatial transcriptomics dataset in Stereoscope.

02 months ago

CondSCVI is a variational inference model for single-cell RNA-seq data that can learn an underlying latent space. The predictions of the model are meant to be afterward used for deconvolution of a second spatial transcriptomics dataset in DestVI.

02 months ago

ScANVI is a variational inference model for single-cell RNA-seq data that can learn an underlying latent space, integrate technical batches and impute dropouts. In addition, to scVI, ScANVI is a semi-supervised model that can leverage labeled data to learn a cell-type classifier in the latent space…

02 months ago